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Growth Hormone Peptides PT - 141 Lyophilized Bremelanotide CAS 189691-06-3

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Growth Hormone Peptides PT - 141 Lyophilized Bremelanotide CAS 189691-06-3

Brand Name : Biopro
Model Number : PEP-106
Certification : GMP/HACCP/ISO
Place of Origin : China
MOQ : 10 vials
Price : USD1~100/vial
Payment Terms : T/T, Western Union, MoneyGram
Supply Ability : 1000 boxes/week
Delivery Time : Immediate Shipment
Packaging Details : 10 vials/box
Product Name : PT-141
Other Name : Bremelanotide
Chemical Name : PT-141 Acetate
Abbreviation : PT141
CAS No. : 189691-06-3
Molecular Formula : C50H68N14O10
Product Type : Product Type
Package : 10 mg/vial
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Lyophilized Peptide PT - 141 CAS 32780-32-8 Bremelanotide as Growth Hormone Peptide


  • Description

    PT-141 (Bremelanotide) is a highly potent synthetic peptide analogue of α-MSH that may elicit aphrodisiac effects through stimulation of melanocortin receptors. PT-141 (Bremelanotide) consists of seven amino acids and is a cyclic, shortened lactam variant of alpha-Melanocyte-stimulating hormone (α-MSH), a multifunctional peptide that regulates a broad array of physiological functions. In studies, bremelanotide was shown to induce lordosis in an animal model and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).
  • Specification

    Name: PT-141
    Synonyms: Bremelanotide, PT-141 Acetate
    CAS #: 189691-06-3
    Molecular Formula: C50H68N14O10
    Molecular Mass: 1025.2 Da (g/mol)
    Amino Acid Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
    Structure:


  • Purity

    PT-141 has a peptide purity level that exceeds 99.0% as determined by HPLC and MS. This peptide was synthesized with no additives and is supplied as a white lyophilized (freeze-dried) powder.


  • Application Information

    Bremelanotide, similarly to its analogues α-MSH and melanotan II, acts as a non-selective agonist of all of the melanocortin receptors except MC2, where it lacks significant affinity. Reported activity of the drug is as follows:
    MC1 (Ki = 0.68 nM)
    MC2 (Ki > 1000 nM)
    MC3 (Ki = 72.07 nM)
    MC4 (Ki = 19.25 nM)
    MC5 (Ki = 166.8 nM)

    Bremelanotide appears to stimulate sexual desire and arousal completely or mostly via activation of the MC4 receptor (the MC3 receptor may also be involved). It modulates inflammation and limits ischemia via activation of the MC1 and MC4 receptors.

    According to Palatin Technologies' original 2003 patent for bremelanotide, it possesses approximately 50 times the potency of melanotan II as an inducer of erection in male rats. In addition, it was stated in the patent that the therapeutic window of bremelanotide in animals (specifically, the range of induction of the desired sexual arousal relative to the induction of side effects including nausea, yawning, stretching, and decreased appetite) was >1,000-fold, whereas that of melanotan II was only 3- to 4-fold. They concluded that bremelanotide would be more tolerable than melanotan II.
  • Buy PT-141 (PT141) from Biopro with discount for the first order
  • Reference List of Available Peptides
    PeptideSpecificationPeptideSpecification
    ACE-9311 mgSemorelin2 mg
    AOD-96045 mgTB-5005 mg
    BPC-1575 mgTesamorelin10 mg
    CJC-1295 DAC2 mgTriptorein2 mg
    CJC-1295 no DAC2 mgMelanotan I10 mg
    Epithalon10 mgMelanotan II10 mg
    FST-3441 mgPT-14110 mg
    Fragment 176-1915 mgMGF2 mg
    GHRP-25 mgPEG-MGF2 mg
    GHRP-65 mgSelank5 mg
    Gonadorelin10 mgDSIP2 mg
    Hexarelin2 mgIGF-1 LR30.1 mg
    Ipamorelin2 mgIGF-1 (1-3)1 mg
    Oxytocin10 mgSNAP-8200 mg


Product Tags:

Growth Hormone Releasing Peptide

      

Peptide Growth Hormone

      
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